Iran may become the center of challenges in Middle East for outbreak of delta variant-COVID-19

During the past three decades, Middle East has been one of important areas that experienced major viral epidemics. COVID-19 as a pulmonary disease was first reported in China early third decade 21st century and quickly infected Asian countries, East, then entire world. The pandemic caused widespread financial damage life-threatening, but exact extent is still unclear. high prevalence created fright public societies disrupted many everyday tasks. various clinical symptoms are updated daily by different researchers. Many countries do not have sufficient tools to prevent, identify treat virus challenges controlling disease. where Iran under heavy economic political sanctions, faced deaths due lack facilities. These affected only also neighboring other related countries. Recently, concerns doubled with outbreak delta variant-COVID-19 because risk hospitalization rate spread higher. purpose this review present latest on symptoms, pathogenicity host immune responses, Etiology Epidemiology, transmission routes impact Eastern especially Iran, its role